Article

Barking Up the Right Tree: Immune Checkpoint Signatures of Human and Dog Cancers

2024-06-29

Abstract excerpt

In the quest for improved therapeutics targeting immune checkpoints (ICs), we turn to spontaneously developing dog (canine) cancers, which are unique models that genetically and clinically mirror human equivalents. Despite its potential, canine cancer immunology remains largely unexplored. Here, we examine the RNA-seq-based expression of 44 ICs across 14 canine cancer types and an extensive human dataset. We unvei...

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Identifiers and source

Literature Corpus work: 25ee6713-6f36-564a-91df-54515862d745
DOI: 10.1101/2024.06.26.600825

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