Article

Circulating Tumor DNA-Based Copy-Number Profiles Enable Monitoring Treatment Effects During Therapy in High-Grade Serous Carcinoma

2023-07-07

Abstract excerpt

<h4>Background: </h4> Circulating tumor DNA (ctDNA) analysis has emerged as a promising tool for detecting and profiling longitudinal genomic changes in cancer. While copy-number alterations (CNAs) play a major role in cancers, monitoring treatment effects using copy-number profiles has received limited attention compared to mutations. This is primarily due to the challenge of CNA analysis for real-life tumor-frac...

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Literature Corpus work: 49ec591a-5777-5829-a7a9-96e110869b07
DOI: 10.21203/rs.3.rs-3127401/v1

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