Article

Tumour informed workflow to use ctDNA as a biomarker for risk of recurrence in head and neck cancer patients post-treatment

2025-07-10

Abstract excerpt

<h4>Background: </h4> Circulating tumour DNA (ctDNA) is a promising minimally invasive biomarker for monitoring treatment response in cancer patients. In this study, we developed a tumour-informed workflow to enhance the detection of recurrence in head and neck cancer (HNC) patients, addressing challenges of low ctDNA tumour fractions and heterogeneity. <h4>Method:</h4> Patient-derived tumour tissues (N=12), perip...

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Literature Corpus work: 2c0013b9-24ec-5356-b1b5-9151b81b9029
DOI: 10.22541/au.175214185.57554698/v1

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