Article

Multi-Omics Characterization of ctDNA Release Mechanisms in Ovarian Cancer

2025-08-06

Abstract excerpt

Circulating tumor DNA (ctDNA) is a powerful biomarker capable to predict tumor dynamics and treatment response. Despite its importance, the biological mechanisms behind ctDNA release have remained unclear. The variability among patients is affected by cancer burden, histology and stage, but these factors cover only a part of the detected variability. Herein, we characterized molecular drivers of baseline ctDNA var...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2f2ea706-9cfa-524f-97ec-edb5b4cf932b
DOI: 10.1101/2025.08.03.668326

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-Omics Characterization of ctDNA Release Mechanisms in Ovarian CancerDOI 10.1101/2025.08.03.668326Read

Circulating tumor DNA: a noninvasive biomarker for tracking ovarian cancerSemantic proximity Read

Current Applications and Challenges of Next-Generation Sequencing in Plasma Circulating Tumour DNA of Ovarian CancerSemantic proximity Read

Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevanceSemantic proximity Read

Single-cell RNA sequencing reveals that MYBL2 in malignant epithelial cells is involved in the development and progression of ovarian cancerSemantic proximity Read

Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinomaSemantic proximity Read

Integrated analysis of spatial transcriptomics and CT phenotypes for unveiling the novel molecular characteristics of recurrent and non-recurrent high-grade serous ovarian cancerSemantic proximity Read

Circulating Tumor DNA (ctDNA) and Its Role in Gynecologic Malignancies.Semantic proximity Read

Tissue architecture and immune niches govern ctDNA release in colorectal cancerSemantic proximity Read

Single-Cell Dissection of the Multiomic Landscape of High-Grade Serous Ovarian CancerSemantic proximity Read

Advances in application of circulating tumor DNA in ovarian cancer.Semantic proximity Read

Genomic and TCR profiling data reveal the distinct molecular traits in epithelial ovarian cancer histotypes.Semantic proximity Read

Spatial transcriptomics reveals ovarian cancer subclones with distinct tumour microenvironmentsSemantic proximity Read