Article

Uncovering cryptic pockets in the SARS-CoV-2 spike glycoprotein

2021-05-05

Abstract excerpt

<h4>ABSTRACT</h4> The recent global COVID-19 pandemic has prompted a rapid response in terms of vaccine and drug development targeting the viral pathogen, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this work, we modelled a complete membrane-embedded SARS-CoV-2 spike (S) protein, the primary target of vaccine and therapeutics development, based on available structural data and known glycan co...

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Literature Corpus work: 49e427c5-6aaa-5ce2-b1a5-ccdac3fb9f18
DOI: 10.1101/2021.05.05.442536

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