MicroRNAs in Osteoclastogenesis and Function: Potential Therapeutic Targets for Osteoporosis

Abstract excerpt

Abnormal osteoclast formation and resorption play a fundamental role in osteoporosis pathogenesis. Over the past two decades, much progress has been made to target osteoclasts. The existing therapeutic drugs include bisphosphonates, hormone replacement therapy, selective estrogen receptor modulators, calcitonin and receptor activator of nuclear factor NF-κB ligand (RANKL) inhibitor (denosumab), etc. Among them,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone and Joint Diseases
• Share to Bone Metabolism and Diseases
• Share to MicroRNA in disease regulation