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Predicting the Purity of Multispecific Antibodies From Sequence Using Machine Learning: Methods and Applications

2023-12-07

Abstract excerpt

Multispecific antibodies are prominent therapeutic agents, but many molecular formats and drug candidates that show promise during molecular discovery stages cannot be scaled up and developed into drugs due to inadequate developability. During the discovery stages, the selection of molecule format(s), molecule design, purity, and initial physiochemical stability testing criteria largely rely on scientists’ experie...

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Literature Corpus work
499b93c7-d0dd-590c-93b0-82a21904df0d
DOI
10.1101/2023.12.05.570217
Open publication

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Predicting the Purity of Multispecific Antibodies From Sequence Using Machine Learning: Methods and ApplicationsDOI 10.1101/2023.12.05.570217
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