Article

Novel insights into phage biology of the pathogen <i>Clostridioides difficile</i> based on the active virome

2023-09-27

Abstract excerpt

The global pathogen Clostridioides difficile is a well-studied organism, and researchers work on unravelling its fundamental virulence mechanisms and biology. Prophages have been demonstrated to influence C. difficile toxin expression and contribute to the distribution of advantageous genes. All this underlines the importance of prophages in C. difficile virulence. Although several C. difficile prophages were...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3d8f4187-46a1-599f-83cf-20fa6915ae62
DOI: 10.1101/2023.09.27.559748

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Novel insights into phage biology of the pathogen <i>Clostridioides difficile</i> based on the active viromeDOI 10.1101/2023.09.27.559748Read

Clostridioides difficile phage biology and applicationSemantic proximity Read

Bacteriophages Contribute to Shaping Clostridioides (Clostridium) difficile SpeciesSemantic proximity Read

The phi027 Bacteriophage Influences Physiology and Virulence of the Lysogenic Strain of <em>Clostridioides difficile</em>Semantic proximity Read

Prophage Carriage and Genetic Diversity within Environmental Isolates of Clostridioides difficile.Semantic proximity Read

Characterization of Bacteriophages Infecting Clinical Isolates of Clostridium difficileSemantic proximity Read

High Prevalence and Genetic Diversity of Large phiCD211 (phiCDIF1296T)-Like Prophages in Clostridioides difficile.Semantic proximity Read

Clostridium difficile phages: still difficult?Semantic proximity Read

Evidence of in vivo prophage induction during Clostridium difficile infection.Semantic proximity Read

Phage transcriptional regulator X (PtrX)-mediated augmentation of toxin production and virulence in <i>Clostridioides difficile</i> strain R20291Semantic proximity Read

Type I toxin-antitoxin systems contribute to mobile genetic elements maintenance in <i>Clostridioides difficile</i> and can be used as a counter-selectable marker for chromosomal manipulationSemantic proximity Read

Isolation and Characterization of the Novel Phage JD032 and Global Transcriptomic Response during JD032 Infection of Clostridioides difficile Ribotype 078Semantic proximity Read

Isolation and Characterization of Temperate Bacteriophages of <i>Clostridium difficile</i>Semantic proximity Read