Article

Multiarmed DNA jumper and Metal-Organic Frameworks–Functionalized Paper-based Bioplatform for Small Extracellular Vesicle–derived miRNAs Assay

2023-08-25

Abstract excerpt

Small extracellular vesicle–derived microRNAs (sEV-miRNAs) have emerged as promising noninvasive biomarkers for early cancer diagnosis. Herein, we developed a molecular probe based on three-dimensional (3D) multiarmed DNA tetrahedral jumpers (mDNA-Js)-assisted DNAzyme activated by Na + , combined with a disposable paper-based electrode modified with a Zr-MOF–rGO–Au NP nanocomplex (ZrGA) to fabricate a novel biosen...

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Literature Corpus work: 4977e25d-c0cb-571e-bf32-39eb3c47b4b8
DOI: 10.21203/rs.3.rs-3279256/v1

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