Article

Suppression of host gene expression is associated with latent TB infection: a possible diagnostic biomarker

2024-05-02

Abstract excerpt

<title>Abstract</title> <p>The World Health Organization End TB strategy aims for a 90% reduction of tuberculosis (TB) incidence by 2035. Systematic testing and treatment of latent TB infection (LTBI) among contacts of active TB (ATB) patients is recommended as one of the ways to curtail TB incidence. However, there is a shortage of tools to accurately diagnose LTBI. We assessed the appropriateness of whole blood...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 490fae48-ab57-5da2-a5b6-c0f03b56c30d
DOI: 10.21203/rs.3.rs-4049377/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Suppression of host gene expression is associated with latent TB infection: a possible diagnostic biomarkerDOI 10.21203/rs.3.rs-4049377/v1Read

Specific human gene expression in response to infection is an effective marker for diagnosis of latent and active tuberculosisSemantic proximity Read

Real-time PCR for the rapid identification of latent tuberculosis infection using host-serum biomarkersSemantic proximity Read

Identification of host gene expression biomarkers for tuberculosisSemantic proximity Read

Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active TuberculosisSemantic proximity Read

Systematic Expression Profiling Analysis Identifies Specific MicroRNA-Gene Interactions that May Differentiate between Active and Latent Tuberculosis InfectionSemantic proximity Read

A blood RNA transcript signature for TB exposure in household contactsSemantic proximity Read

Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individualsSemantic proximity Read

Transcriptional Profiling of Human Peripheral Blood Mononuclear Cells Identifies Diagnostic Biomarkers That Distinguish Active and Latent TuberculosisSemantic proximity Read

Uncovering Immune Response Landscapes and Novel Biomarkers in Latent Endometrial Tuberculosis: Insights from RNA-Seq Transcriptome ProfilingSemantic proximity Read

Immune Subtyping in Latent Tuberculosis.Semantic proximity Read

Diagnosing tuberculosis using nanomaterial-based detection of a host gene expression signatureSemantic proximity Read

Persistent DNA Hyper-methylation Dampens Host Anti-Mycobacterial ImmunitySemantic proximity Read