Article

Leveraging a Billion-Edge Knowledge Graph for Drug Re-purposing and Target Prioritization using Genomically-Informed Subgraphs

2022-12-20

Abstract excerpt

Drug development is a resource and time-intensive process resulting in attrition rates of up to 90%. As a result, repurposing existing drugs with established safety and pharmacokinetic profiles is gaining traction as a way of accelerating therapeutics development. Here we have developed unique machine learning-driven Natural Language Processing and biomedical semantic technologies that mine over 53 million biomedi...

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Literature Corpus work: 05a0bd88-2fca-5f19-b11d-aaf284c53a4e
DOI: 10.1101/2022.12.20.521235

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