Article

Correlation Between TGF-β1 and c-MET Expression in HCV Genotype 4-Induced Liver Fibrosis

2018-12-01

Abstract excerpt

Although direct-acting antiviral agents (DAAs) provide hopes for diminution of hepatitis C virus (HCV)-induced liver fibrosis, understanding the molecular mechanisms of crosstalk between signaling pathways in fibrogenesis has remained challenging. In this study, we hypothesize that the mesenchymal–epithelial transition factor (c-MET) and transforming growth factor-β1 (TGF-β1) pathways perform antagonistic function...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 48f2bbc9-0cb2-5320-86e7-8fc8ac01fadf
DOI: 10.1089/jir.2018.0096

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Correlation Between TGF-β1 and c-MET Expression in HCV Genotype 4-Induced Liver FibrosisDOI 10.1089/jir.2018.0096Read

Identification of TAF1, HNF4A, and CALM2 as potential therapeutic target genes for liver fibrosisSemantic proximity Read

Cytokine/chemokine patterns connect host and viral characteristics with clinics during chronic hepatitis C.Semantic proximity Read

miR-98-5p as a novel biomarker suppress liver fibrosis by targeting TGFβ receptor 1Semantic proximity Read

The dichotomous role of TGF-β in controlling liver cancer cell survival and proliferationSemantic proximity Read

Extrahepatic Upregulation of Transforming Growth Factor Beta 2 in HCV Genotype 4-Induced Liver Fibrosis.Semantic proximity Read

The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC ActivationSemantic proximity Read

miR-98-5p as a Novel Biomarker Suppress Liver Fibrosis by Targeting TGFβ Receptor 1Semantic proximity Read

Roles of TGF-beta in hepatic fibrosisSemantic proximity Read

TGF-β signaling pathway as a pharmacological target in liver diseasesSemantic proximity Read

Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progressionSemantic proximity Read

Balance Between EGF/STAT1 and IFNγ/NRF2 Signaling Controls ECM1 Expression and Determines Hepatic Homeostasis versus Chronic Liver DiseaseSemantic proximity Read

Alanine aminotransferase, HCV RNA levels and pro-inflammatory and pro-fibrogenic cytokines/chemokines during acute hepatitis C virus infection.Semantic proximity Read