Article
Cytokine/chemokine patterns connect host and viral characteristics with clinics during chronic hepatitis C.
European journal of medical research - 11 May 2012
Katsounas Antonios, Trippler Martin, Kottilil Shyam, Lempicki Richard A, Gerken Guido, Schlaak Joerg F
Abstract excerpt
BACKGROUND: In chronic hepatitis C virus (HCV) infection, liver tissue pathology and HCV genotype are important determinants of clinical and/or treatment-related outcome. Although consistent epidemiological and/or molecular-biological clues derived from different studies on single virus-host interactions are meanwhile published, the in vivo transcriptional responses and cellular pathways affected in >1 key...
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