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Article

Extrahepatic Upregulation of Transforming Growth Factor Beta 2 in HCV Genotype 4-Induced Liver Fibrosis.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Aug 2018

Abd El-Meguid Mai, Dawood Reham M, Mokhles Mohamed Aly, El Awady Mostafa K

Abstract excerpt

Elevated levels of transforming growth factor-β (TGF-β) family mediate myofibroblast generation and extracellular matrix deposition, thus making TGF-β recognized as major profibrogenic cytokines. In this article, we provide evidence that extrahepatic TGF-β2 expression at RNA and protein levels in peripheral leucocytes and serum, respectively, correlate with hepatic fibrogenesis. Current study includes a total of...

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Identifiers

PMID: 30130153
DOI: 10.1089/jir.2018.0045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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