Article
Structure and size determination of bacteriophage P2 and P4 procapsids: function of size responsiveness mutations.
Journal of structural biology - 1 Jun 2012
Dearborn Altaira D, Laurinmaki Pasi, Chandramouli Preethi, Rodenburg Cynthia M, Wang Sifang, Butcher Sarah J, Dokland Terje
Abstract excerpt
Bacteriophage P4 is dependent on structural proteins supplied by a helper phage, P2, to assemble infectious virions. Bacteriophage P2 normally forms an icosahedral capsid with T=7 symmetry from the gpN capsid protein, the gpO scaffolding protein and the gpQ portal protein. In the presence of P4, however, the same structural proteins are assembled into a smaller capsid with T=4 symmetry. This size determination is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
