Article

Spatially resolved T cell receptor tracking reveals γδT cell localization to tumor-rich regions in high-risk neuroblastoma: A Report from the Children’s Oncology Group

2026-06-12

Abstract excerpt

High-risk neuroblastoma (HRNB) is a leading cause of pediatric cancer death. Current therapies center on intensive multimodal treatment including anti-GD2 therapy, with growing interest in harnessing T cell-mediated immunity. How T cells and their receptors (T-cell receptors, TCRs) are spatially organized and function within tumors remains poorly defined. To assess whether intratumoral location influences clonotyp...

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Literature Corpus work: 486d4f26-c1d5-5dce-a143-eebaff89de9d
DOI: 10.64898/2026.06.10.26354144

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