Back to search

Article

Exploration of Interethnic Variation in the Ibuprofen Metabolizing Enzyme CYP2C9: A Cautionary Guide for Treatment of COVID-19 Symptoms

2021-02-08

Abstract excerpt

<h4>Background: </h4> Coronavirus disease 2019 (COVID-19), is a rapidly spreading infectious illness that causes a debilitating respiratory syndrome. While non-steroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, may be prescribed for the management of pain and fever, controversy arose on the use of ibuprofen due to the possibility of a worse COVID-19 prognosis. P450 enzyme CYP2C9 are known to be invol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4864383b-ffe6-5841-8e58-c4e36f8e5cbe
DOI
10.21203/rs.3.rs-156293/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Exploration of Interethnic Variation in the Ibuprofen Metabolizing Enzyme&nbsp;CYP2C9: A Cautionary Guide for Treatment of COVID-19 SymptomsDOI 10.21203/rs.3.rs-156293/v1
Exploration of interethnic variation in the ibuprofen metabolizing enzyme CYP2C9: a genetic-based cautionary guide for treatment of COVID-19 symptomsSemantic proximity
Exploration of interethnic variation in the ibuprofen metabolizing enzyme CYP2C9: a cautionary guide for treatment of COVID-19 symptomsSemantic proximity
Exploration of interethnic variation and repurposed drug efficacy in the treatment of SARS-CoV-2 Infection (COVID-19)Semantic proximity
Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2C9 and Nonsteroidal Anti-Inflammatory Drugs.Semantic proximity
How polymorphisms of the cytochrome P450 genes affect ibuprofen and diclofenac metabolism and toxicity.Semantic proximity
Global distribution of CYP2C19 risk phenotypes affecting safety and effectiveness of medications.Semantic proximity
Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?Semantic proximity
Frequencies of CYP2D6 genetic polymorphisms in Arab populations.Semantic proximity
[Clinical pharmacogenomics for CYP2C8 and CYP2C9: general concepts and application to the use of NSAIDs].Semantic proximity
Influence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers.Semantic proximity
Pharmacogenetics Approach for the Improvement of COVID-19 TreatmentSemantic proximity
Possible interethnic differences in omeprazole pharmacokinetics : comparison of Jordanian Arabs with other populations.Semantic proximity
Select a neighboring publication to make it the new centre.