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Comprehensive Evaluation of Polymorphism in SLC11A1 and its Association with Susceptibility to Tuberculosis: A Meta-Analysis

2026-05-26

Abstract excerpt

<title>Abstract</title> <p> Background Tuberculosis (TB) remains the deadliest infectious disease, with about 8 million new cases annually. Since only 10% of the exposed individuals develop active disease, host genetics play a significant role. The SLC11A1 (NRAMP1) gene encodes a macrophage phagosomal iron transporter, central to innate immunity. D543N, 3’UTR TGTG ins/del, INT4 and (GT) <sub>n</sub> polymorph...

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Literature Corpus work
48350145-9fab-5f45-83bc-e40dc98cf5cb
DOI
10.21203/rs.3.rs-9796002/v1
Open publication

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Comprehensive Evaluation of Polymorphism in SLC11A1 and its Association with Susceptibility to Tuberculosis: A Meta-AnalysisDOI 10.21203/rs.3.rs-9796002/v1
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