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Article

SLC11A1 (NRAMP1) polymorphisms and tuberculosis susceptibility: updated systematic review and meta-analysis.

PloS one - 25 Jan 2011

Li XiangWei, Yang Yu, Zhou Feng, Zhang Yunzhi, Lu Hongzhou, Jin Qi, Gao Lei

Abstract excerpt

BACKGROUND: Natural resistance associated macrophage protein 1 (NRAMP1), encoded by the SLC11A1 gene, has been described to regulate macrophage activation and be associated with infectious and autoimmune diseases. The relation between SLC11A1 polymorphisms and tuberculosis susceptibility has been studied in different populations. METHODS: We systematically reviewed published studies on SLC11A1 polymorphisms and...

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PMID: 21283567
DOI: 10.1371/journal.pone.0015831
PMCID: PMC3026788

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