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Article

Polymorphisms of SLC11A1(NRAMP1) rs17235409 associated with and susceptibility to spinal tuberculosis in a southern Han Chinese population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2022

Li Tao, Wang Longjie, Guo Chaofeng, Zhang Hongqi, Xu Peng, Liu Shaohua, Hu Xiaojiang, Gao Qile

Abstract excerpt

OBJECTIVE: To investigate the association between SLC11A1 (NRAMP1) rs17235409 (D543N) polymorphisms and susceptibility to spinal tuberculosis (STB) in the Han population in southern China. METHODS: This study included 227 STB patients and 516 controls. Polymorphisms of SLC11A1 rs17235409 were genotyped using a SNPscan™ kit, and the protein was detected by western blotting. RESULTS: The genotype and allele...

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PMID: 34990850
DOI: 10.1016/j.meegid.2021.105202

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