Article

Gene Expansion and Regulatory Rewiring Shape Sex-Biased Evolution of the Mouse Submandibular Gland Secretome

2026-03-20

Abstract excerpt

<h4>ABSTRACT</h4> Mammalian saliva plays essential roles in digestion, immunity, and host-microbiome interactions, yet its protein composition varies across species and sexes. The evolutionary mechanisms underlying this molecular diversity remain poorly understood. Here, we compared mouse and human salivary gland secretomes at genomic, transcriptomic, and proteomic levels to understand how saliva composition evol...

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Literature Corpus work: a37898aa-2966-57be-86a9-b447da2772b7
DOI: 10.64898/2026.03.18.712472

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