Article

Hepatocyte-derived exosomal microRNAs orchestrate vascular inflammation and endothelial function: insights into molecular mechanisms of trimethylamine-N-Oxide in atherosclerosis

2021-04-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Trimethylamine-N-oxide (TMAO) has been proved to be a new proatherogenic compound for promoting vascular inflammation and endothelial dysfunction. Hepatocyte-derived exosomes played an important role in the regulation of vascular inflammation and endothelial function. Since TMAO is produced in the liver, hepatocytes may be the first potential target of TMAO. How...

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Literature Corpus work: 47ff48ce-0023-5f6c-bd56-cfa86782b0ea
DOI: 10.21203/rs.3.rs-223231/v2

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