Article

TMAO Stimulate Inflammation and Lipid Accumulation via NF-κB Signaling Pathway in Nonalcoholic Fatty Liver Disease

2021-11-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Nonalcoholic fatty liver disease (NAFLD) is a common disease and it is commonly associated with obesity. Trimethylamine N-oxide (TMAO) is a metabolite of intestinal flora generated in liver by flavin-containing monooxygenase 3 (FMO3), which has been widely studied in cardiovascular diseases and obesity. However, the mechanism of TMAO reacted on liver remains uncl...

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Literature Corpus work: 416392f8-ddf6-5584-9ebc-89ebebf184bf
DOI: 10.21203/rs.3.rs-993103/v1

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