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Heterogeneous expression of the atypical chemokine receptor ACKR3 in glioblastoma patient-derived tissue samples and cell cultures.

2024-03-05

Abstract excerpt

<h4>Background: </h4> Glioblastoma (GBM) is the most aggressive glial tumor of the adult brain, associated with invariably fatal outcome, and a deeper understanding of the underlying malignant mechanisms is necessary to address the current therapeutic failure. We previously demonstrated the role of the CXCL12/CXCR4 axis in GBM cell migration and resistance to ionizing radiation. The atypical receptor ACKR3, respon...

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Literature Corpus work
47d188b4-139d-51cb-998c-fb34f85af119
DOI
10.21203/rs.3.rs-3996294/v1
Open publication

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Heterogeneous expression of the atypical chemokine receptor ACKR3 in glioblastoma patient-derived tissue samples and cell cultures.DOI 10.21203/rs.3.rs-3996294/v1
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