Article

A filamentous phage promotes meningococcal colonization by selecting hyperadhesive pili variants linking phage infection to bacterial virulence

2025-01-09

Abstract excerpt

<title>Abstract</title> Filamentous phages belong to Inoviruses, a family of non-lytic phages that are mutually beneficial to their bacterial hosts. These phages have a role in bacterial dissemination, biofilm formation or immune evasion. In Neisseria meningitidis, the strains harbouring the MDA filamentous phage are associated with invasive diseases through the MDAΦ key role in epithelial cell colonisation. U...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 47973dde-7073-5c00-867a-ebda54631168
DOI: 10.21203/rs.3.rs-5633068/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A filamentous phage promotes meningococcal colonization by selecting hyperadhesive pili variants linking phage infection to bacterial virulenceDOI 10.21203/rs.3.rs-5633068/v1Read

Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDAΦSemantic proximity Read

Filamentous Bacteriophage: Biology, Phage Display and Nanotechnology ApplicationsSemantic proximity Read

Antigenic variation impacts gonococcal lifestyle and antibiotic tolerance by modulating interbacterial forcesSemantic proximity Read

Targeting Type IV pili as an antivirulence strategy against invasive meningococcal diseaseSemantic proximity Read

The Clostridioides difficile S-Layer Protein A (SlpA) serves as a general phage receptorSemantic proximity Read

'Big things in small packages: the genetics of filamentous phage and effects on fitness of their host'.Semantic proximity Read

Systematic functional analysis reveals that a set of seven genes is involved in fine-tuning of the multiple functions mediated by type IV pili in Neisseria meningitidis.Semantic proximity Read

Type-4 pili and meningococcal adhesiveness.Semantic proximity Read

Type IV pilus retraction in pathogenic Neisseria is regulated by the PilC proteinsSemantic proximity Read

P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips.Semantic proximity Read

A New Family of Secreted Toxins in Pathogenic Neisseria SpeciesSemantic proximity Read

The meningococcal PilT protein is required for induction of intimate attachment to epithelial cells following pilus-mediated adhesion.Semantic proximity Read