Article
Type-4 pili and meningococcal adhesiveness.
Gene - 11 Jun 1997
Nassif X, Marceau M, Pujol C, Pron B, Beretti J L, Taha M K
Abstract excerpt
The ability to interact with non-phagocytic cells is a crucial virulence attribute of the meningococcus. Pili play a major role in this process and are the only means yet discovered by which capsulated bacteria may adhere to cells. Pilus-mediated adhesion is a two-step process which requires (i) the expression of the adhesin PilC1 and (ii) the expression of an appropriate pilin variant. Some pilin variants have...
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