Article

Antigenic variation impacts gonococcal lifestyle and antibiotic tolerance by modulating interbacterial forces

2023-07-07

Abstract excerpt

Type 4 pili (T4P) are multifunctional filaments involved in adhesion, surface motility, colony formation, and horizontal gene transfer. These extracellular polymers are surface-exposed and, therefore, act as antigens. The human pathogen Neisseria gonorrhoeae uses pilin antigenic variation to escape immune surveillance, yet it is unclear how antigenic variation impacts other functions of T4P. Here, we addressed th...

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Literature Corpus work: acc753c6-405f-55e1-8b39-5a38dc29d799
DOI: 10.1101/2023.07.06.548055

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