Article
'Big things in small packages: the genetics of filamentous phage and effects on fitness of their host'.
FEMS microbiology reviews - 1 Jul 2015
Mai-Prochnow Anne, Hui Janice Gee Kay, Kjelleberg Staffan, Rakonjac Jasna, McDougald Diane, Rice Scott A
Abstract excerpt
This review synthesizes recent and past observations on filamentous phages and describes how these phages contribute to host phentoypes. For example, the CTXφ phage of Vibrio cholerae encodes the cholera toxin genes, responsible for causing the epidemic disease, cholera. The CTXφ phage can transduce non-toxigenic strains, converting them into toxigenic strains, contributing to the emergence of new pathogenic...
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