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Glibenclamide, ATP and Metformin Increases the Expression of Human Bile Salt Export Pump ABCB11

2020-09-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Bile Salt Export Pump (BSEP/ABCB11) is important in the maintenance of the enterohepatic circulation of bile acids and drugs. Drugs such as rifampicin, glibenclamide inhibit BSEP. Progressive Familial Intrahepatic Cholestasis Type-2, a lethal pediatric disease, some forms of intrahepatic cholestasis of pregnancy, and drug-induced cholestasis are associated with BSEP dysfunct...

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Literature Corpus work
47795a5d-f3ab-5e4b-a580-24c8c2f55cdd
DOI
10.1101/2020.09.01.277434
Open publication

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Glibenclamide, ATP and Metformin Increases the Expression of Human Bile Salt Export Pump ABCB11DOI 10.1101/2020.09.01.277434
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