Article

DNA methylation and demethylation driven regulation of sepsis

2024-09-25

Abstract excerpt

During dysregulated inflammation and sepsis, there is a sudden surge of cytokines, such as TNF alpha, IL6, and IL10, which disrupts the body homeostasis. This sudden and rapid increase in cytokine gene expression cannot be explained by the conventional central dogma mechanism. DNA methylation is one of the most significant epigenetic modifications. DNA methylation is mostly associated with the suppression of gene...

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Literature Corpus work: 46f850d0-1164-59ce-9178-24a6097851be
DOI: 10.1101/2024.09.25.614895

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