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The Epigenetics of Sepsis: How Gene Modulation Shapes Outcomes

8 Aug 2025

Abstract excerpt

Sepsis is a complex and heterogeneous condition, arising from a disrupted immune response to infection that can progress to organ failure and carries a high risk of death. In recent years, growing attention has been paid to the role of epigenetic mechanisms—including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation—in shaping immune activity during sepsis. These processes affect immune...

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PMID: 40868190
DOI: 10.3390/biomedicines13081936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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