Article

Classification of <i>ACE</i> variants related to Alzheimer’s disease (AD): the <i>ACE</i> mutations — AD browser

2026-08-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> ACE variants are genetic risk factors for Alzheimer’s disease (AD), potentially through reduced enzymatic activity and impaired amyloid-β hydrolysis. <h4>Objectives</h4> To create a publicly available database of ACE variants relevant to ACE deficiency and AD, and to estimate the population frequency of damaging ACE variants and their impact on blood ACE levels. <h4>Met...

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Literature Corpus work: 46e59fd4-ebc8-5f30-ac65-5a825954f3af
DOI: 10.64898/2026.08.09.26360046

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