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Article

Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin.

Journal of virology - 16 Apr 2024

Wen Feng, Yan Zhanfei, Chen Gaojie, Chen Yao, Wang Nina, Li Zhili, Guo Jinyue, Yu Hai, Liu Quan, Huang Shujian

Abstract excerpt

The H9N2 avian influenza virus (AIV) represents a significant risk to both the poultry industry and public health. Our surveillance efforts in China have revealed a growing trend of recent H9N2 AIV strains exhibiting a loss of hemagglutination activity at 37°C, posing challenges to detection and monitoring protocols. This study identified a single K141N substitution in the hemagglutinin (HA) glycoprotein as the...

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Identifiers

PMID: 38466094
DOI: 10.1128/jvi.00248-24
PMCID: PMC11019909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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