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Article

Immune escape mutants of Highly Pathogenic Avian Influenza H5N1 selected using polyclonal sera: identification of key amino acids in the HA protein.

PloS one - 1 Jan 2014

Sitaras Ioannis, Kalthoff Donata, Beer Martin, Peeters Ben, de Jong Mart C M

Abstract excerpt

Evolution of Avian Influenza (AI) viruses--especially of the Highly Pathogenic Avian Influenza (HPAI) H5N1 subtype--is a major issue for the poultry industry. HPAI H5N1 epidemics are associated with huge economic losses and are sometimes connected to human morbidity and mortality. Vaccination (either as a preventive measure or as a means to control outbreaks) is an approach that splits the scientific community,...

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Identifiers

PMID: 24586231
DOI: 10.1371/journal.pone.0084628
PMCID: PMC3934824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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