Article

NK cells control the progression of myelodysplastic syndrome but become initial disease target in <i>NUP98-HOXD13</i> mouse model

2024-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Studies in NUP98/HOXD13 mouse model (NHD13 tg ), progressing from myelodysplastic syndrome (MDS) to different forms of leukemia, demonstrated that T cells had a limited anti-leukemia effect, suggesting the involvement of other immune cells. Natural killer (NK) cells control viral infection and cancer. In MDS and acute myeloid leukemia (AML), patients often acquire disease-induced NK cell dysfu...

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Literature Corpus work: 46d03239-0f22-5e05-b6fe-4f600694af23
DOI: 10.1101/2024.12.11.627924

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