Article

Chlamydial YAP activation in host endocervical epithelial cells mediates pro-fibrotic paracrine stimulation of fibroblasts

2023-05-31

Abstract excerpt

Infection of the female genital tract by Chlamydia trachomatis can produce severe fibrotic sequelae, including tubal factor infertility and ectopic pregnancy. While infection demonstrably mediates a pro-fibrotic response in host cells, it remains unclear if intrinsic properties of the upper genital tract exacerbate chlamydial fibrosis. The relatively sterile environment of the upper genital tract is primed for a...

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Literature Corpus work: 46c3a840-89fb-5dd0-aa66-fa4475e4b90d
DOI: 10.1101/2023.05.30.542940

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Chlamydial YAP activation in host endocervical epithelial cells mediates pro-fibrotic paracrine stimulation of fibroblastsDOI 10.1101/2023.05.30.542940Read

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