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Article

Suppression of Gremlin by RNA interference attenuates glucose-induced fibrogenesis in rat mesangial cells

2020-01-22

Abstract excerpt

<title>Abstract</title> <p>Background: diabetic nephropathy (DN) is the most common cause of end-stage of renal disease. It is beneficial for us to find effective way to treat the disease. Gremlin is deemed as a key factor in the development of diabetic nephropathy at present. We hypothesized that the pathological changes might be prevented by eliminating Gremlin function in high glucose-induced renal fibrosis. <...

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Literature Corpus work
466eeb6d-e2b8-5b69-88c5-fcc155f35947
DOI
10.21203/rs.2.21574/v1
Open publication

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