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Article

A pathway phenotype linking metabolic, immune, oxidative, and opioid pathways with comorbid depression, atherosclerosis, and unstable angina.

CNS spectrums - 1 Dec 2022

Mousa Rana Fadhil, Smesam Hasan Najah, Qazmooz Hasan Abbas, Al-Hakeim Hussein Kadhem, Maes Michael

Abstract excerpt

BACKGROUND: There is strong comorbidity between atherosclerosis (ATS) and depression which is attributed to increased atherogenicity, insulin resistance (IR), and immune and oxidative stress. AIM OF THE STUDY: To examine the role of the above pathways and mu-opioid receptor (MOR), β-endorphin levels, zinc, copper, vitamin D3, calcium, and magnesium in depression due to ATS/unstable angina (UA). METHODS:...

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Identifiers

PMID: 34039448
DOI: 10.1017/S1092852921000432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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