Article

Lymphocytic Profile and Ebv Serology in Sjögren’s Syndrome: Evidences for a Virally Triggered Autoimmune Epithelitis?

2020-11-25

Abstract excerpt

Sjögren's Syndrome (SjS) is characterized by lymphocytic infiltration of exocrine glands, i.e. autoimmune epithelitis. Lymphocytes are central in SjS pathogenesis, with B-cell hyperactivity mediated by T-cells. B-cells are main targets of Epstein-Barr virus (EBV) infection, a frequently-suggested trigger for SjS.We aimed to evaluate how the EBV infection modulates B and T-cell subsets in SjS, including as controls...

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Literature Corpus work: 462b4691-6b6c-51cf-8a25-8ce65ff60221
DOI: 10.21203/rs.3.rs-109255/v1

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