Article
A comprehensive review of autoantibodies in primary Sjögren's syndrome: clinical phenotypes and regulatory mechanisms.
Journal of autoimmunity - 1 Jun 2014
Kyriakidis Nikolaos C, Kapsogeorgou Efstathia K, Tzioufas Athanasios G
Abstract excerpt
Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by periepithelial lymphocytic infiltrates in affected tissues and the production of plethora of autoantibodies. Among them autoimmune responses against Ro/SSA and La/SSB are of major importance since their detection is routinely used for disease diagnosis and clinical characterization. Although the exact mechanisms underlying disease...
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