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Article

CD8+ T Lymphocytes: Crucial Players in Sjögren's Syndrome.

Frontiers in immunology - 1 Jan 2020

Zhou Huimin, Yang Jun, Tian Jie, Wang Shengjun

Abstract excerpt

Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease associated with damage to multiple organs and glands. The most common clinical manifestations are dry eyes, dry mouth, and enlarged salivary glands. Currently, CD4+ T lymphocytes are considered to be key factors in the immunopathogenesis of pSS, but various studies have shown that CD8+ T lymphocytes contribute to acinar injury in the exocrine...

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Identifiers

PMID: 33584670
DOI: 10.3389/fimmu.2020.602823
PMCID: PMC7876316

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