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Serum preprocessing workflows differentially shape biological readout in data-independent acquisition proteomics of systemic juvenile idiopathic arthritis

2026-08-17

Abstract excerpt

Serum proteomics is increasingly used for minimally invasive biomarker discovery and disease phenotyping, and the choice of serum preprocessing workflow can shape proteome depth, quantitative characteristics, and downstream biological readouts. However, disease-oriented comparisons within a single cohort remain limited. Here, we compared four serum preprocessing workflows—Top14 depletion (TOP14D), tomato lectin af...

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Identifiers and source

Literature Corpus work
4609463b-2090-5efa-b0d5-61606e34f757
DOI
10.64898/2026.08.15.745022
Open publication

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Serum preprocessing workflows differentially shape biological readout in data-independent acquisition proteomics of systemic juvenile idiopathic arthritisDOI 10.64898/2026.08.15.745022
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