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Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children

5 Jun 2024

Abstract excerpt

Multisystem inflammatory syndrome in children (MIS-C) is a severe disease that emerged during the COVID-19 pandemic. Although recognized as an immune-mediated condition, the pathogenesis remains unresolved. Furthermore, the absence of a diagnostic test can lead to delayed immunotherapy. Using state-of-the-art mass-spectrometry proteomics, assisted by artificial intelligence (AI), we aimed to identify a diagnostic...

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PMID: 38839859
DOI: 10.1038/s42003-024-06370-8

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