Article

Serum proteome analysis of systemic JIA and related pulmonary alveolar proteinosis identifies distinct inflammatory programs and biomarkers

2021-01-26

Abstract excerpt

<h4>Objectives</h4> Recent observations in systemic Juvenile Idiopathic Arthritis (sJIA) suggest an increasing incidence of high-mortality interstitial lung disease, characterized by a variant of pulmonary alveolar proteinosis (PAP). Co-occurrence of macrophage activation syndrome (MAS) and PAP in sJIA suggested a shared pathology, but sJIA-PAP patients also commonly experience features of drug reaction such as at...

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Literature Corpus work: 80951108-4be4-5ad9-8b7c-d493756d2b03
DOI: 10.1101/2021.01.20.21250141

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