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Article

Interferon regulatory factor 7 impairs cellular metabolism in aging adipose-derived stromal cells

30 Apr 2021

Abstract excerpt

Dysregulated immunity and widespread metabolic dysfunctions are the most relevant hallmarks of the passing of time over the course of adult life, and their combination at midlife is strongly related to increased vulnerability to diseases; however, the causal connection between them remains largely unclear. By combining multi-omics and functional analyses of adipose-derived stromal cells established from young (1...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 34096605
DOI: 10.1242/jcs.256230

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