Article

Bruton’s tyrosine kinase (BTK) regulates myeloid cell recruitment during acute inflammation

2021-05-03

Abstract excerpt

Bruton’s tyrosine kinase (BTK) is a non-receptor kinase best known for its role in B lymphocyte development that is critical for proliferation, and survival of leukaemia cells in B cell malignancies. However, BTK is expressed in myeloid cells, particularly monocytes and macrophages where its inhibition has been reported to exhibit anti-inflammatory properties. Therefore, we explored the role of BTK on the migratio...

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Literature Corpus work: 45f27beb-27ab-5922-8bb7-7d3221816d67
DOI: 10.22541/au.162003905.59954600/v1

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