Article

A lignan from Alnus japonica inhibits glioblastoma tumorspheres by suppression of FOXM1

2021-11-23

Abstract excerpt

<title>Abstract</title> <p>Introduction Glioblastoma (GBM) is the most common and aggressive malignant brain tumor. Forkhead Box M1 (FOXM1) has been shown to regulate cell proliferation, apoptosis, angiogenesis, DNA damage repair and tumorigenesis. The lignin, (−)-(2R,3R)-1,4-O-diferuloylsecoisolariciresinol (DFS), from <italic>Alnus japonica</italic> (Betulaceae) has shown anti-cancer effects against colon canc...

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Literature Corpus work: 45d25c7a-7280-5604-bfd0-5ebb074df4b9
DOI: 10.21203/rs.3.rs-1084999/v1

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