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Oleanolic Acid Inhibits the Proliferation and Invasion of U251Glioma Cells and Promotes their Apoptosis through the IKK-β, MAPK3, and MAPK4 Signaling Pathway

2021-09-20

Abstract excerpt

<title>Abstract</title> <p><bold>Object:</bold> To investigate the effects of Oleanolic acid (OA) on proliferation, apoptosis, migration, and invasion of human glioma cell U251, as well as IKK-<italic>β</italic> and MAPK signaling pathways.<bold>Methods:</bold> The binding of OA to IKK-<italic>β</italic> and MAPK signaling pathway essential proteins IKK-<italic>β</italic>, MAPK3, and MAPK4 was analyzed by molecul...

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Literature Corpus work
58dd31a7-8e04-5dc9-88a8-a160beaa9251
DOI
10.21203/rs.3.rs-877888/v1
Open publication

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Oleanolic Acid Inhibits the Proliferation and Invasion of U251Glioma Cells and Promotes their Apoptosis through the IKK-β, MAPK3, and MAPK4 Signaling PathwayDOI 10.21203/rs.3.rs-877888/v1
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