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Identification and drug-induced reversion of molecular signatures of Alzheimer’s disease onset and progression in <i> App <sup>NL-G-F</sup> </i> , <i> App <sup>NL-F</sup> </i> and 3xTg-AD mouse models

2021-03-17

Abstract excerpt

Alzheimer’s disease (AD) is the most common form of dementia. Over fifty years of intense research have revealed many key elements of the biology of this neurodegenerative disorder. However, our understanding of the molecular bases of the disease is still incomplete, and the medical treatments available for AD are mainly symptomatic and hardly effective. Indeed, the robustness of biological systems has revealed th...

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Literature Corpus work
45bfc627-3b1f-572c-b8e8-16c86530ae77
DOI
10.1101/2021.03.17.435753
Open publication

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Identification and drug-induced reversion of molecular signatures of Alzheimer’s disease onset and progression in <i> App <sup>NL-G-F</sup> </i> , <i> App <sup>NL-F</sup> </i> and 3xTg-AD mouse modelsDOI 10.1101/2021.03.17.435753
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