Article

Genetic analysis of low-grade adenosquamous carcinoma of the breast that progressed to high-grade metaplastic carcinoma

2022-09-01

Abstract excerpt

<title>Abstract</title> <p>Low-grade adenosquamous carcinoma (LGASC) is a rare type of metaplastic carcinoma of the breast (MBC) with an indolent clinical course. A few cases with high-grade transformation have been reported; however, their genetic alterations remain unclear. This study was designed to explore the somatic genetic characteristics of LGASC with transformation to high-grade MBC. Whole-genome sequenc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 45afef37-4ced-5a48-8325-fa5b5ffd60d9
DOI: 10.21203/rs.3.rs-1982650/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of low-grade adenosquamous carcinoma of the breast that progressed to high-grade metaplastic carcinomaDOI 10.21203/rs.3.rs-1982650/v1Read

High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast.Semantic proximity Read

Genetic profile of adenoid cystic carcinomas (ACC) with high-grade transformation versus solid type.Semantic proximity Read

Genetic Profiling in Heterogeneous High-Grade Adenoid Cystic Carcinoma Identifies NOTCH1 Inhibition as a Therapeutic StrategySemantic proximity Read

Comprehensive analyses of genomic features and mutational signatures in adenosquamous carcinoma of the lungSemantic proximity Read

Deciphering the clonal relationship between glandular and squamous components in adenosquamous carcinoma of the lung using whole exome sequencingSemantic proximity Read

CDKN2A loss and PIK3CA mutation in myoepithelial-like metaplastic breast cancer.Semantic proximity Read

Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity.Semantic proximity Read

Microglandular adenosis associated with triple-negative breast cancer is a neoplastic lesion of triple-negative phenotype harbouring TP53 somatic mutations.Semantic proximity Read

High-grade Müllerian Adenosarcoma: Genomic and Clinicopathologic Characterization of a Distinct Neoplasm With Prevalent TP53 Pathway Alterations and Aggressive Behavior.Semantic proximity Read

The clinical behavior and genomic features of the so-called adenoid cystic carcinomas of the solid variant with basaloid featuresSemantic proximity Read

Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple‐negative and basal‐like breast cancersSemantic proximity Read